Origins of chromosome translocations in childhood leukaemia
Origins of chromosome translocations in childhood leukaemia
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Different subtypes of leukaemia have distinctive chromosome translocations.
Translocations seem to arise at the level of haematopoietic stem cells, but their impact is cell-context dependent, resulting in different effects in different lineages.
Chromosome translocations are initiated by double-strand DNA breaks. The main repair...
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Origins of chromosome translocations in childhood leukaemia
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TN_cdi_proquest_miscellaneous_73616167
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_73616167
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ISSN
1474-175X
E-ISSN
1474-1768
DOI
10.1038/nrc1164
