Deletion of active ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis
Deletion of active ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Osteoarthritis: a joint effort
The degradation of cartilage in arthritic joints is associated with loss of aggrecan, a large aggregating proteoglycan, and for many years researchers have sought the ‘aggrecanase’ responsible. Two groups now report success: the enzyme ADAMTS5 (also known as aggrecanase-2) is shown to be the primary aggrecanase in...
Alternative Titles
Full title
Deletion of active ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_743165350
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_743165350
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature03369
