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Alzheimer's Disease: The Amyloid Cascade Hypothesis

Alzheimer's Disease: The Amyloid Cascade Hypothesis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_743274724

Alzheimer's Disease: The Amyloid Cascade Hypothesis

About this item

Full title

Alzheimer's Disease: The Amyloid Cascade Hypothesis

Publisher

Washington, DC: American Society for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 1992-04, Vol.256 (5054), p.184-185

Language

English

Formats

Publication information

Publisher

Washington, DC: American Society for the Advancement of Science

More information

Scope and Contents

Contents

Alzheimer's disease causes dementia and is characterized by various pathological markers in the brain. A hypothesis that deposition of amyloid beta protein is the causative agent of Alzheimer's pathology and that the neurofibrillary tangles, cell loss, vascular damage and dementia are a direct result of the protein is examined.

Alternative Titles

Full title

Alzheimer's Disease: The Amyloid Cascade Hypothesis

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_743274724

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_743274724

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.1566067

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