Nuclear Actin Regulates Dynamic Subcellular Localization and Activity of the SRF Cofactor MAL
Nuclear Actin Regulates Dynamic Subcellular Localization and Activity of the SRF Cofactor MAL
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Washington, DC: American Association for the Advancement of Science
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English
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Washington, DC: American Association for the Advancement of Science
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Contents
Actin, which is best known as a cytoskeletal component, also participates in the control of gene expression. We report a function of nuclear actin in the regulation of MAL, a coactivator of the transcription factor serum response factor (SRF). MAL, which binds monomeric actin, is cytoplasmic in many cells but accumulates in the nucleus upon serum-i...
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Full title
Nuclear Actin Regulates Dynamic Subcellular Localization and Activity of the SRF Cofactor MAL
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TN_cdi_proquest_miscellaneous_743315810
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_743315810
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ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1141084
