Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b
Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b
About this item
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Author / Creator
Bachmaier, Kurt , Krawczyk, Connie , Kozieradzki, Ivona , Kong, Young-Yun , Sasaki, Takehiko , Oliveira-dos-Santos, Antonio , Mariathasan, Sanjeev , Bouchard, Dennis , Wakeham, Andrew , Itie, Annick , Le, Jenny , Ohashi, Pamela S. , Sarosi, Ildiko , Nishina, Hiroshi , Lipkowitz, Stan and Penninger, Josef M.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
Subjects
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Scope and Contents
Contents
The signalling thresholds of antigen receptors and co-stimulatory receptors determine immunity or tolerance to self molecules
1
. Changes in co-stimulatory pathways can lead to enhanced activation of lymphocytes and autoimmunity, or the induction of clonal anergy
2
. The molecular mechanisms that maintain immunotolerance
in vivo
a...
Alternative Titles
Full title
Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b
Authors, Artists and Contributors
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Record Identifier
TN_cdi_proquest_miscellaneous_743324563
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_743324563
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/35003228
