Preferential Generation of Follicular B Helper T Cells from Foxp3⁺ T Cells in Gut Peyer's Patches
Preferential Generation of Follicular B Helper T Cells from Foxp3⁺ T Cells in Gut Peyer's Patches
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Washington, DC: American Association for the Advancement of Science
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English
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Washington, DC: American Association for the Advancement of Science
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Contents
Most of the immunoglobulin A (IgA) in the gut is generated by B cells in the germinal centers of Peyer's patches through a process that requires the presence of CD4⁺ follicular B helper T(TFH) cells. The nature of these TFH cells in Peyer's patches has been elusive. Here, we demonstrate that suppressive Foxp3⁺CD4⁺ T cells can differentiate into TFH...
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Preferential Generation of Follicular B Helper T Cells from Foxp3⁺ T Cells in Gut Peyer's Patches
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TN_cdi_proquest_miscellaneous_743388101
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_743388101
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ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1169152