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Preferential Generation of Follicular B Helper T Cells from Foxp3⁺ T Cells in Gut Peyer's Patches

Preferential Generation of Follicular B Helper T Cells from Foxp3⁺ T Cells in Gut Peyer's Patches

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_743388101

Preferential Generation of Follicular B Helper T Cells from Foxp3⁺ T Cells in Gut Peyer's Patches

About this item

Full title

Preferential Generation of Follicular B Helper T Cells from Foxp3⁺ T Cells in Gut Peyer's Patches

Publisher

Washington, DC: American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 2009-03, Vol.323 (5920), p.1488-1492

Language

English

Formats

Publication information

Publisher

Washington, DC: American Association for the Advancement of Science

More information

Scope and Contents

Contents

Most of the immunoglobulin A (IgA) in the gut is generated by B cells in the germinal centers of Peyer's patches through a process that requires the presence of CD4⁺ follicular B helper T(TFH) cells. The nature of these TFH cells in Peyer's patches has been elusive. Here, we demonstrate that suppressive Foxp3⁺CD4⁺ T cells can differentiate into TFH...

Alternative Titles

Full title

Preferential Generation of Follicular B Helper T Cells from Foxp3⁺ T Cells in Gut Peyer's Patches

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_743388101

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_743388101

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.1169152

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