Proliferation of Functional Hair Cells in vivo in the Absence of the Retinoblastoma Protein
Proliferation of Functional Hair Cells in vivo in the Absence of the Retinoblastoma Protein
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Washington, DC: American Association for the Advancement of Science
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English
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Washington, DC: American Association for the Advancement of Science
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In mammals, hair cell loss causes irreversible hearing and balance impairment because hair cells are terminally differentiated and do not regenerate spontaneously. By profiling gene expression in developing mouse vestibular organs, we identified the retinoblastoma protein (pRb) as a candidate regulator of cell cycle exit in hair cells. Differentiat...
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Proliferation of Functional Hair Cells in vivo in the Absence of the Retinoblastoma Protein
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TN_cdi_proquest_miscellaneous_743388643
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_743388643
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ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1106642