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Proliferation of Functional Hair Cells in vivo in the Absence of the Retinoblastoma Protein

Proliferation of Functional Hair Cells in vivo in the Absence of the Retinoblastoma Protein

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_743388643

Proliferation of Functional Hair Cells in vivo in the Absence of the Retinoblastoma Protein

About this item

Full title

Proliferation of Functional Hair Cells in vivo in the Absence of the Retinoblastoma Protein

Publisher

Washington, DC: American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 2005-02, Vol.307 (5712), p.1114-1118

Language

English

Formats

Publication information

Publisher

Washington, DC: American Association for the Advancement of Science

More information

Scope and Contents

Contents

In mammals, hair cell loss causes irreversible hearing and balance impairment because hair cells are terminally differentiated and do not regenerate spontaneously. By profiling gene expression in developing mouse vestibular organs, we identified the retinoblastoma protein (pRb) as a candidate regulator of cell cycle exit in hair cells. Differentiat...

Alternative Titles

Full title

Proliferation of Functional Hair Cells in vivo in the Absence of the Retinoblastoma Protein

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_743388643

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_743388643

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.1106642

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