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Protein Kinase G from Pathogenic Mycobacteria Promotes Survival within Macrophages

Protein Kinase G from Pathogenic Mycobacteria Promotes Survival within Macrophages

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_743394093

Protein Kinase G from Pathogenic Mycobacteria Promotes Survival within Macrophages

About this item

Full title

Protein Kinase G from Pathogenic Mycobacteria Promotes Survival within Macrophages

Publisher

Washington, DC: American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 2004-06, Vol.304 (5678), p.1800-1804

Language

English

Formats

Publication information

Publisher

Washington, DC: American Association for the Advancement of Science

Subjects

Subjects and topics

More information

Scope and Contents

Contents

Pathogenic mycobacteria resist lysosomal delivery after uptake into macrophages, allowing them to survive intracellularly. We found that the eukaryotic-like serine/threonine protein kinase G from pathogenic mycobacteria was secreted within macrophage phagosomes, inhibiting phagosome-lysosome fusion and mediating intracellular survival of mycobacter...

Alternative Titles

Full title

Protein Kinase G from Pathogenic Mycobacteria Promotes Survival within Macrophages

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_743394093

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_743394093

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.1099384

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