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ArticlesPeer ReviewedFull Text
The challenge of new drug discovery for tuberculosis
Author / Creator:Koul, Anil ; Arnoult, Eric ; Lounis, Nacer ; Guillemont, Jerome ; Andries, Koen
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2011-01, Vol.469 (7331), p.483-490
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Acquired resistance of Mycobacterium tuberculosis to bedaquiline
Author / Creator:Andries, Koen ; Villellas, Cristina ; Coeck, Nele ; Thys, Kim ; Gevers, Tom ; Vranckx, Luc ; Lounis, Nacer ; de Jong, Bouke C ; Koul, Anil
Publisher:United States: Public Library of Science
Journal title:PloS one, 2014-07, Vol.9 (7), p.e102135
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Molecular mechanism of respiratory syncytial virus fusion inhibitors
Author / Creator:Battles, Michael B ; Langedijk, Johannes P ; Furmanova-Hollenstein, Polina ; Chaiwatpongsakorn, Supranee ; Costello, Heather M ; Kwanten, Leen ; Vranckx, Luc ; Vink, Paul ; Jaensch, Steffen ; Jonckers, Tim H M ; Koul, Anil ; Arnoult, Eric ; Peeples, Mark E ; Roymans, Dirk ; McLellan, Jason S
Publisher:New York: Nature Publishing Group US
Journal title:Nature chemical biology, 2016-02, Vol.12 (2), p.87-93
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The cytochrome bd-type quinol oxidase is important for survival of Mycobacterium smegmatis under peroxide and antibiotic-induced stress
Author / Creator:Lu, Ping ; Heineke, Marieke H. ; Koul, Anil ; Andries, Koen ; Cook, Gregory M. ; Lill, Holger ; van Spanning, Rob ; Bald, Dirk
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2015-05, Vol.5 (1), p.10333-10333, Article 10333
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Probing the interaction of the diarylquinoline TMC207 with its target mycobacterial ATP synthase
Author / Creator:Haagsma, Anna C ; Podasca, Ioana ; Koul, Anil ; Andries, Koen ; Guillemont, Jerome ; Lill, Holger ; Bald, Dirk
Publisher:United States: Public Library of Science
Journal title:PloS one, 2011-08, Vol.6 (8), p.e23575
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Author Correction: An open-access dashboard to interrogate the genetic diversity of Mycobacterium tuberculosis clinical isolates
Author / Creator:Phelan, Jody ; Van den Heede, Klaas ; Masyn, Serge ; Verbeeck, Rudi ; Clark, Taane G. ; Lamprecht, Dirk A. ; Koul, Anil ; Wall, Richard J.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2025-04, Vol.15 (1), p.11565-1, Article 11565
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An open-access dashboard to interrogate the genetic diversity of Mycobacterium tuberculosis clinical isolates
Author / Creator:Phelan, Jody ; Van den Heede, Klaas ; Masyn, Serge ; Verbeeck, Rudi ; Clark, Taane G. ; Lamprecht, Dirk A. ; Koul, Anil ; Wall, Richard J.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2024-10, Vol.14 (1), p.24792-9, Article 24792
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Therapeutic efficacy of a respiratory syncytial virus fusion inhibitor
Author / Creator:Roymans, Dirk ; Alnajjar, Sarhad S ; Battles, Michael B ; Sitthicharoenchai, Panchan ; Furmanova-Hollenstein, Polina ; Rigaux, Peter ; Berg, Joke Van den ; Kwanten, Leen ; Ginderen, Marcia Van ; Verheyen, Nick ; Vranckx, Luc ; Jaensch, Steffen ; Arnoult, Eric ; Voorzaat, Richard ; Gallup, Jack M. ; Larios-Mora, Alejandro ; Crabbe, Marjolein ; Huntjens, Dymphy ; Raboisson, Pierre ; Langedijk, Johannes P. ; Ackermann, Mark R. ; McLellan, Jason S ; Vendeville, Sandrine ; Koul, Anil
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2017-08, Vol.8 (1), p.167-15, Article 167
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Newsletter articlesFull Text
Guillemont Jer?me Emile Georges, Lan?ois David Francis Alain, Motte Magali Madeleine Simone, Koul Anil, Balemans Wendy Mia Albert, Arnoult Eric Pierre Alexandre and Janssen RD Ireland Submit Patent Ap...
Publisher:New Delhi: Pedia Content Solutions Pvt. Ltd
Journal title:Global IP News. Pharmaceutical Patent News, 2014
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Newsletter articlesFull Text
Guillemont Jer?me Emile Georges, Lan?ois David Francis Alain, Motte Magali Madeleine Simone, Koul Anil and Balemans Wendy Mia Albert Apply for Patent on Antibacterial Piperidinyl Substituted 3,4-Dihyd...
Publisher:New Delhi: Pedia Content Solutions Pvt. Ltd
Journal title:Global IP News. Pharmaceutical Patent News, 2014
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ArticlesPeer ReviewedFull Text
Protein Kinase G from Pathogenic Mycobacteria Promotes Survival within Macrophages
Author / Creator:Walburger, Anne ; Koul, Anil ; Ferrari, Giorgio ; Nguyen, Liem ; Prescianotto-Baschong, Cristina ; Huygen, Kris ; Klebl, Bert ; Thompson, Charles ; Bacher, Gerald ; Pieters, Jean
Publisher:Washington, DC: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2004-06, Vol.304 (5678), p.1800-1804
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ArticlesPeer ReviewedFull Text
Antiviral Activity of TMC353121, a Respiratory Syncytial Virus (RSV) Fusion Inhibitor, in a Non-Human Primate Model
Author / Creator:Ispas, Gabriela ; Koul, Anil ; Verbeeck, Johan ; Sheehan, Jennifer ; Sanders-Beer, Brigitte ; Roymans, Dirk ; Andries, Koen ; Rouan, Marie-Claude ; De Jonghe, Sandra ; Bonfanti, Jean-François ; Vanstockem, Marc ; Simmen, Kenneth ; Verloes, Rene
Publisher:United States: Public Library of Science
Journal title:PloS one, 2015-05, Vol.10 (5), p.e0126959-e0126959
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ArticlesPeer ReviewedFull Text
The ATP synthase inhibitor bedaquiline interferes with small-molecule efflux in Mycobacterium smegmatis
Author / Creator:Lu, Ping ; Villellas, Cristina ; Koul, Anil ; Andries, Koen ; Lill, Holger ; Bald, Dirk
Publisher:London: Nature Publishing Group UK
Journal title:Journal of antibiotics, 2014-12, Vol.67 (12), p.835-837
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ArticlesPeer ReviewedFull Text
PGC-1α Thr394Thr and Gly482Ser variants are significantly associated with T2DM in two North Indian populations : a replicate case-control study
Author / Creator:BHAT, Audesh ; KOUL, Anil ; RAI, Ekta ; SHARMA, Swarkar ; DHAR, M. K ; BAMEZAI, R. N. K
Publisher:Heidelberg: Springer
Journal title:Human genetics, 2007-06, Vol.121 (5), p.609-614
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The possible role of 10398A and 16189C mtDNA variants in providing susceptibility toT2DM in two North Indian populations : a replicative study
Author / Creator:BHAT, Audesh ; KOUL, Anil ; SHARMA, Swarkar ; RAI, Ekta ; BUKHARI, S. I. A ; DHAR, M. K ; BAMEZAI, R. N. K
Publisher:Heidelberg: Springer
Journal title:Human genetics, 2007-02, Vol.120 (6), p.821-826
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ArticlesPeer ReviewedFull Text
Respiratory ATP synthesis: the new generation of mycobacterial drug targets
Author / Creator:Bald, Dirk ; Koul, Anil
Publisher:Oxford, UK: Oxford, UK : Blackwell Publishing Ltd
Journal title:FEMS microbiology letters, 2010-07, Vol.308 (1), p.1-7
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ArticlesPeer ReviewedFull Text
Essentiality of FASII pathway for Staphylococcus aureus
Author / Creator:Balemans, Wendy ; Lounis, Nacer ; Gilissen, Ron ; Guillemont, Jerome ; Simmen, Kenny ; Andries, Koen ; Koul, Anil
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2010-01, Vol.463 (7279), p.E3-E3
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ArticlesPeer ReviewedFull Text
Delayed bactericidal response of Mycobacterium tuberculosis to bedaquiline involves remodelling of bacterial metabolism
Author / Creator:Koul, Anil ; Vranckx, Luc ; Dhar, Neeraj ; Göhlmann, Hinrich W.H. ; Özdemir, Emre ; Neefs, Jean-Marc ; Schulz, Melanie ; Lu, Ping ; Mørtz, Ejvind ; McKinney, John D. ; Andries, Koen ; Bald, Dirk
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2014-02, Vol.5 (1), p.3369, Article 3369
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ArticlesPeer ReviewedFull Text
Diarylquinolines target subunit c of mycobacterial ATP synthase
Author / Creator:Koul, Anil ; Dendouga, Najoua ; Vergauwen, Karen ; Molenberghs, Brenda ; Vranckx, Luc ; Willebrords, Rudy ; Ristic, Zorica ; Lill, Holger ; Dorange, Ismet ; Guillemont, Jerome ; Bald, Dirk ; Andries, Koen
Publisher:New York: Nature Publishing Group US
Journal title:Nature chemical biology, 2007-06, Vol.3 (6), p.323-324
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ArticlesPeer ReviewedFull Text
Antiviral Activity of Oral JNJ-53718678 in Healthy Adult Volunteers Challenged With Respiratory Syncytial Virus: A Placebo-Controlled Study
Author / Creator:Stevens, Marita ; Rusch, Sarah ; DeVincenzo, John ; Kim, Young-In ; Harrison, Lisa ; Meals, Elizabeth A ; Boyers, Alison ; Fok-Seang, Juin ; Huntjens, Dymphy ; Lounis, Nacer ; Mari N, Kris ; Remmerie, Bart ; Roymans, Dirk ; Koul, Anil ; Verloes, René
Publisher:United States
Journal title:The Journal of infectious diseases, 2018-07, Vol.218 (5), p.748-756
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Showing 1 to 20 of 30 results

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The challenge of new drug discovery for tuberculosis

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Acquired resistance of Mycobacterium tuberculosis to bedaquiline

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Molecular mechanism of respiratory syncytial virus fusion inhibitors

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The cytochrome bd-type quinol oxidase is important for survival of Mycobacterium smegmatis under peroxide and antibiotic-induced stress

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Probing the interaction of the diarylquinoline TMC207 with its target mycobacterial ATP synthase

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Author Correction: An open-access dashboard to interrogate the genetic diversity of Mycobacterium tuberculosis clinical isolates

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An open-access dashboard to interrogate the genetic diversity of Mycobacterium tuberculosis clinical isolates

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Therapeutic efficacy of a respiratory syncytial virus fusion inhibitor

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Guillemont Jer?me Emile Georges, Lan?ois David Francis Alain, Motte Magali Madeleine Simone, Koul Anil, Balemans Wendy Mia Albert, Arnoult Eric Pierre Alexandre and Janssen RD Ireland Submit Patent Ap...

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Guillemont Jer?me Emile Georges, Lan?ois David Francis Alain, Motte Magali Madeleine Simone, Koul Anil and Balemans Wendy Mia Albert Apply for Patent on Antibacterial Piperidinyl Substituted 3,4-Dihyd...

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Protein Kinase G from Pathogenic Mycobacteria Promotes Survival within Macrophages

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Antiviral Activity of TMC353121, a Respiratory Syncytial Virus (RSV) Fusion Inhibitor, in a Non-Human Primate Model

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The ATP synthase inhibitor bedaquiline interferes with small-molecule efflux in Mycobacterium smegmatis

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PGC-1α Thr394Thr and Gly482Ser variants are significantly associated with T2DM in two North Indian populations : a replicate case-control study

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The possible role of 10398A and 16189C mtDNA variants in providing susceptibility toT2DM in two North Indian populations : a replicative study

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Respiratory ATP synthesis: the new generation of mycobacterial drug targets

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Essentiality of FASII pathway for Staphylococcus aureus

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Delayed bactericidal response of Mycobacterium tuberculosis to bedaquiline involves remodelling of bacterial metabolism

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Diarylquinolines target subunit c of mycobacterial ATP synthase

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Antiviral Activity of Oral JNJ-53718678 in Healthy Adult Volunteers Challenged With Respiratory Syncytial Virus: A Placebo-Controlled Study

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