Optimal isotope labelling for NMR protein structure determinations
Optimal isotope labelling for NMR protein structure determinations
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Nuclear-magnetic-resonance spectroscopy can determine the three-dimensional structure of proteins in solution. However, its potential has been limited by the difficulty of interpreting NMR spectra in the presence of broadened and overlapping resonance lines and low signal-to-noise ratios. Here we present stereo-array isotope labelling (SAIL), a tec...
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Optimal isotope labelling for NMR protein structure determinations
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TN_cdi_proquest_miscellaneous_743408981
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_743408981
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ISSN
0028-0836
E-ISSN
1476-4687,1476-4679
DOI
10.1038/nature04525