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Sortilin is essential for proNGF-induced neuronal cell death

Sortilin is essential for proNGF-induced neuronal cell death

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_743473081

Sortilin is essential for proNGF-induced neuronal cell death

About this item

Full title

Sortilin is essential for proNGF-induced neuronal cell death

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2004-02, Vol.427 (6977), p.843-848

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Sortilin
1
(∼95 kDa) is a member of the recently discovered family of Vps10p-domain receptors
2
,
3
, and is expressed in a variety of tissues, notably brain, spinal cord and muscle. It acts as a receptor for neurotensin
4
,
5
, but predominates in regions of the nervous system that neither synthesize nor respond to th...

Alternative Titles

Full title

Sortilin is essential for proNGF-induced neuronal cell death

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_743473081

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_743473081

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/nature02319

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