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Crystal Structure of a Mammalian Fatty Acid Synthase

Crystal Structure of a Mammalian Fatty Acid Synthase

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_743500739

Crystal Structure of a Mammalian Fatty Acid Synthase

About this item

Full title

Crystal Structure of a Mammalian Fatty Acid Synthase

Publisher

Washington, DC: American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 2008-09, Vol.321 (5894), p.1315-1322

Language

English

Formats

Publication information

Publisher

Washington, DC: American Association for the Advancement of Science

More information

Scope and Contents

Contents

Mammalian fatty acid synthase is a large multienzyme that catalyzes all steps of fatty acid synthesis. We have determined its crystal structure at 3.2 angstrom resolution covering five catalytic domains, whereas the flexibly tethered terminal acyl carrier protein and thioesterase domains remain unresolved. The structure reveals a complex architectu...

Alternative Titles

Full title

Crystal Structure of a Mammalian Fatty Acid Synthase

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_743500739

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_743500739

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.1161269

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