A Toll-like receptor recognizes bacterial DNA
A Toll-like receptor recognizes bacterial DNA
About this item
Full title
A Toll-like receptor recognizes bacterial DNA
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Nature (London), 2000-12, Vol.408 (6813), p.740-745
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
DNA from bacteria has stimulatory effects on mammalian immune cells
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, which depend on the presence of unmethylated CpG dinucleotides in the bacterial DNA. In contrast, mammalian DNA has a low frequency of CpG dinucleotides, and these are mostly methylated; therefore, mammalian DNA does not have immuno-stimulatory activit...
Alternative Titles
Full title
A Toll-like receptor recognizes bacterial DNA
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_743524792
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_743524792
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/35047123
