Tauopathy in Drosophila: Neurodegeneration without Neurofibrillary Tangles
Tauopathy in Drosophila: Neurodegeneration without Neurofibrillary Tangles
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Washington, DC: American Society for the Advancement of Science
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Language
English
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Publisher
Washington, DC: American Society for the Advancement of Science
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Contents
The microtubule-binding protein tau has been implicated in the pathogenesis of Alzheimer's disease and related disorders. However, the mechanisms underlying tau-mediated neurotoxicity remain unclear. We created a genetic model of tau-related neurodegenerative disease by expressing wild-type and mutant forms of human tau in the fruit fly Drosophila...
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Full title
Tauopathy in Drosophila: Neurodegeneration without Neurofibrillary Tangles
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TN_cdi_proquest_miscellaneous_743535695
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_743535695
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ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1062382
