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Caspase-1 processes IFN-γ-inducing factor and regulates LPS-induced IFN- γ production

Caspase-1 processes IFN-γ-inducing factor and regulates LPS-induced IFN- γ production

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_743655550

Caspase-1 processes IFN-γ-inducing factor and regulates LPS-induced IFN- γ production

About this item

Full title

Caspase-1 processes IFN-γ-inducing factor and regulates LPS-induced IFN- γ production

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 1997-04, Vol.386 (6625), p.619-623

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Interferon-γ-inducing factor (IGIF, interleukin-18) is a recently described cytokine that shares structural features with the inter-leukin-1 (IL-1) family of proteins and functional properties with IL-12
1–4
. Like IL-12, IGIF is a potent inducer of interferon (IFN)-γ from T cells and natural killer cells
1–3,5,6
. IGIF is synthesized a...

Alternative Titles

Full title

Caspase-1 processes IFN-γ-inducing factor and regulates LPS-induced IFN- γ production

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_743655550

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_743655550

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/386619a0

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