Divergent Immunoglobulin G Subclass Activity Through Selective Fc Receptor Binding
Divergent Immunoglobulin G Subclass Activity Through Selective Fc Receptor Binding
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Author / Creator
Publisher
Washington, DC: American Association for the Advancement of Science
Journal title
Language
English
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Publication information
Publisher
Washington, DC: American Association for the Advancement of Science
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Scope and Contents
Contents
Subclasses of immunoglobulin G (IgG) display substantial differences in their ability to mediate effector responses, contributing to variable activity of antibodies against microbes and tumors. We demonstrate that the mechanism underlying this long-standing observation of subclass dominance in function is provided by the differential affinities of...
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Full title
Divergent Immunoglobulin G Subclass Activity Through Selective Fc Receptor Binding
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Record Identifier
TN_cdi_proquest_miscellaneous_744717540
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_744717540
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1118948
