Fragment C of tetanus toxin, more than a carrier. Novel perspectives in non-viral ALS gene therapy
Fragment C of tetanus toxin, more than a carrier. Novel perspectives in non-viral ALS gene therapy
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Publisher
Berlin/Heidelberg: Springer-Verlag
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Language
English
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Publisher
Berlin/Heidelberg: Springer-Verlag
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Contents
The non-toxic carboxy-terminal fragment of tetanus toxin heavy chain (TTC) has been implicated in the activation of cascades responsible for trophic actions and neuroprotection by inhibition of apoptosis. Previous in vitro studies have described signalling pathways that underlie the administration of TTC to neurons. We investigated whether these pr...
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Full title
Fragment C of tetanus toxin, more than a carrier. Novel perspectives in non-viral ALS gene therapy
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Record Identifier
TN_cdi_proquest_miscellaneous_745929795
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_745929795
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ISSN
0946-2716
E-ISSN
1432-1440
DOI
10.1007/s00109-009-0556-y