When does brain aging accelerate? Dangers of quadratic fits in cross-sectional studies
When does brain aging accelerate? Dangers of quadratic fits in cross-sectional studies
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United States: Elsevier Inc
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Language
English
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Publisher
United States: Elsevier Inc
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Contents
Many brain structures show a complex, non-linear pattern of maturation and age-related change. Often, quadratic models (β0+β1age+β2age2+ε) are used to describe such relationships. Here, we demonstrate that the fitting of quadratic models is substantially affected by seemingly irrelevant factors, such as the age-range sampled. Hippocampal volume was...
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When does brain aging accelerate? Dangers of quadratic fits in cross-sectional studies
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TN_cdi_proquest_miscellaneous_745930887
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_745930887
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ISSN
1053-8119
E-ISSN
1095-9572
DOI
10.1016/j.neuroimage.2010.01.061