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When does brain aging accelerate? Dangers of quadratic fits in cross-sectional studies

When does brain aging accelerate? Dangers of quadratic fits in cross-sectional studies

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_745930887

When does brain aging accelerate? Dangers of quadratic fits in cross-sectional studies

About this item

Full title

When does brain aging accelerate? Dangers of quadratic fits in cross-sectional studies

Publisher

United States: Elsevier Inc

Journal title

NeuroImage (Orlando, Fla.), 2010-05, Vol.50 (4), p.1376-1383

Language

English

Formats

Publication information

Publisher

United States: Elsevier Inc

More information

Scope and Contents

Contents

Many brain structures show a complex, non-linear pattern of maturation and age-related change. Often, quadratic models (β0+β1age+β2age2+ε) are used to describe such relationships. Here, we demonstrate that the fitting of quadratic models is substantially affected by seemingly irrelevant factors, such as the age-range sampled. Hippocampal volume was...

Alternative Titles

Full title

When does brain aging accelerate? Dangers of quadratic fits in cross-sectional studies

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_745930887

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_745930887

Other Identifiers

ISSN

1053-8119

E-ISSN

1095-9572

DOI

10.1016/j.neuroimage.2010.01.061

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