hERG potassium channels and cardiac arrhythmia
hERG potassium channels and cardiac arrhythmia
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
hERG potassium channels are essential for normal electrical activity in the heart. Inherited mutations in the
HERG
gene cause long QT syndrome, a disorder that predisposes individuals to life-threatening arrhythmias. Arrhythmia can also be induced by a blockage of hERG channels by a surprisingly diverse group of drugs. This side effect is a c...
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Full title
hERG potassium channels and cardiac arrhythmia
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TN_cdi_proquest_miscellaneous_746227897
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_746227897
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ISSN
0028-0836
E-ISSN
1476-4687,1476-4679
DOI
10.1038/nature04710