Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer suscept...
Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene
About this item
Full title
Author / Creator
Meindl, Alfons , Hellebrand, Heide , Wiek, Constanze , Erven, Verena , Wappenschmidt, Barbara , Niederacher, Dieter , Freund, Marcel , Lichtner, Peter , Hartmann, Linda , Schaal, Heiner , Ramser, Juliane , Honisch, Ellen , Kubisch, Christian , Wichmann, Hans E , Kast, Karin , Deißler, Helmut , Engel, Christoph , Müller-Myhsok, Bertram , Neveling, Kornelia , Kiechle, Marion , Mathew, Christopher G , Schindler, Detlev , Schmutzler, Rita K and Hanenberg, Helmut
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Alfons Meindl and colleagues report heterozygous germline mutations in
RAD51C
in families with breast and ovarian cancer. Mutations were found in 1.3% of 480 pedigrees with breast and ovarian cancer, but not in 620 pedigrees with breast cancer only.
Germline mutations in a number of genes involved in the recombinational repair of DNA doubl...
Alternative Titles
Full title
Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene
Authors, Artists and Contributors
Author / Creator
Hellebrand, Heide
Wiek, Constanze
Erven, Verena
Wappenschmidt, Barbara
Niederacher, Dieter
Freund, Marcel
Lichtner, Peter
Hartmann, Linda
Schaal, Heiner
Ramser, Juliane
Honisch, Ellen
Kubisch, Christian
Wichmann, Hans E
Kast, Karin
Deißler, Helmut
Engel, Christoph
Müller-Myhsok, Bertram
Neveling, Kornelia
Kiechle, Marion
Mathew, Christopher G
Schindler, Detlev
Schmutzler, Rita K
Hanenberg, Helmut
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_746234230
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_746234230
Other Identifiers
ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/ng.569
