Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NLRP3 inflammasome
Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NLRP3 inflammasome
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London: BMJ Publishing Group Ltd and British Society of Gastroenterology
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English
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London: BMJ Publishing Group Ltd and British Society of Gastroenterology
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BackgroundThe proinflammatory cytokines interleukin 1β (IL-1β) and IL-18 are central players in the pathogenesis of inflammatory bowel disease (IBD). In response to a variety of microbial components and crystalline substances, both cytokines are processed via the caspase-1-activating multiprotein complex, the NLRP3 inflammasome. Here, the role of t...
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Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NLRP3 inflammasome
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TN_cdi_proquest_miscellaneous_749008811
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_749008811
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ISSN
0017-5749
E-ISSN
1468-3288
DOI
10.1136/gut.2009.197822
