Sequencing of 50 Human Exomes Reveals Adaptation to High Altitude
Sequencing of 50 Human Exomes Reveals Adaptation to High Altitude
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Author / Creator
Yi, Xin , Liang, Yu , Huerta-Sanchez, Emilia , Jin, Xin , Cuo, Zha Xi Ping , Pool, John E , Xu, Xun , Jiang, Hui , Vinckenbosch, Nicolas , Korneliussen, Thorfinn Sand , Zheng, Hancheng , Liu, Tao , He, Weiming , Li, Kui , Luo, Ruibang , Nie, Xifang , Wu, Honglong , Zhao, Meiru , Cao, Hongzhi , Zou, Jing , Shan, Ying , Li, Shuzheng , Yang, Qi , Asan , Ni, Peixiang , Tian, Geng , Xu, Junming , Liu, Xiao , Jiang, Tao , Wu, Renhua , Zhou, Guangyu , Tang, Meifang , Qin, Junjie , Wang, Tong , Feng, Shuijian , Li, Guohong , Huasang , Luosang, Jiangbai , Wang, Wei , Chen, Fang , Wang, Yading , Zheng, Xiaoguang , Li, Zhuo , Bianba, Zhuoma , Yang, Ge , Wang, Xinping , Tang, Shuhui , Gao, Guoyi , Chen, Yong , Luo, Zhen , Gusang, Lamu , Cao, Zheng , Zhang, Qinghui , Ouyang, Weihan , Ren, Xiaoli , Liang, Huiqing , Zheng, Huisong , Huang, Yebo , Li, Jingxiang , Bolund, Lars , Kristiansen, Karsten , Li, Yingrui , Zhang, Yong , Zhang, Xiuqing , Li, Ruiqiang , Li, Songgang , Yang, Huanming , Nielsen, Rasmus , Wang, Jun and Wang, Jian
Publisher
United States: American Association for the Advancement of Science
Journal title
Language
English
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Publication information
Publisher
United States: American Association for the Advancement of Science
Subjects
More information
Scope and Contents
Contents
Residents of the Tibetan Plateau show heritable adaptations to extreme altitude. We sequenced 50 exomes of ethnic Tibetans, encompassing coding sequences of 92% of human genes, with an average coverage of 18x per individual. Genes showing population-specific allele frequency changes, which represent strong candidates for altitude adaptation, were i...
Alternative Titles
Full title
Sequencing of 50 Human Exomes Reveals Adaptation to High Altitude
Authors, Artists and Contributors
Author / Creator
Liang, Yu
Huerta-Sanchez, Emilia
Jin, Xin
Cuo, Zha Xi Ping
Pool, John E
Xu, Xun
Jiang, Hui
Vinckenbosch, Nicolas
Korneliussen, Thorfinn Sand
Zheng, Hancheng
Liu, Tao
He, Weiming
Li, Kui
Luo, Ruibang
Nie, Xifang
Wu, Honglong
Zhao, Meiru
Cao, Hongzhi
Zou, Jing
Shan, Ying
Li, Shuzheng
Yang, Qi
Asan
Ni, Peixiang
Tian, Geng
Xu, Junming
Liu, Xiao
Jiang, Tao
Wu, Renhua
Zhou, Guangyu
Tang, Meifang
Qin, Junjie
Wang, Tong
Feng, Shuijian
Li, Guohong
Huasang
Luosang, Jiangbai
Wang, Wei
Chen, Fang
Wang, Yading
Zheng, Xiaoguang
Li, Zhuo
Bianba, Zhuoma
Yang, Ge
Wang, Xinping
Tang, Shuhui
Gao, Guoyi
Chen, Yong
Luo, Zhen
Gusang, Lamu
Cao, Zheng
Zhang, Qinghui
Ouyang, Weihan
Ren, Xiaoli
Liang, Huiqing
Zheng, Huisong
Huang, Yebo
Li, Jingxiang
Bolund, Lars
Kristiansen, Karsten
Li, Yingrui
Zhang, Yong
Zhang, Xiuqing
Li, Ruiqiang
Li, Songgang
Yang, Huanming
Nielsen, Rasmus
Wang, Jun
Wang, Jian
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_753662452
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_753662452
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1190371
