Endogenous antibodies promote rapid myelin clearance and effective axon regeneration after nerve inj...
Endogenous antibodies promote rapid myelin clearance and effective axon regeneration after nerve injury
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Degenerating myelin inhibits axon regeneration and is rapidly cleared after peripheral (PNS) but not central nervous system (CNS) injury. To better understand mechanisms underlying rapid PNS myelin clearance, we tested the potential role of the humoral immune system. Here, we show that endogenous antibodies are required for rapid and robust PNS mye...
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Full title
Endogenous antibodies promote rapid myelin clearance and effective axon regeneration after nerve injury
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TN_cdi_proquest_miscellaneous_754537072
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_754537072
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1001948107