Structural basis for Rab GTPase recognition and endosome tethering by the C sub(2)H sub(2) zinc fing...
Structural basis for Rab GTPase recognition and endosome tethering by the C sub(2)H sub(2) zinc finger of Early Endosomal Autoantigen 1 (EEA1)
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English
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Regulation of endosomal trafficking by Rab GTPases depends on selective interactions with multivalent effectors, including EEA1 and Rabenosyn-5, which facilitate endosome tethering, sorting, and fusion. Both EEA1 and Rabenosyn-5 contain a distinctive N-terminal C sub(2)H sub(2) zinc finger that binds Rab5. How these C sub(2)H sub(2) zinc fingers re...
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Structural basis for Rab GTPase recognition and endosome tethering by the C sub(2)H sub(2) zinc finger of Early Endosomal Autoantigen 1 (EEA1)
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TN_cdi_proquest_miscellaneous_754538251
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_754538251
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ISSN
0027-8424
DOI
10.1073/pnas.1000843107
