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ArticlesPeer ReviewedFull Text
Preclinical Activity of ARQ 087, a Novel Inhibitor Targeting FGFR Dysregulation
Author / Creator:Hall, Terence G. ; Yu, Yi ; Eathiraj, Sudharshan ; Wang, Yunxia ; Savage, Ronald E. ; Lapierre, Jean-Marc ; Schwartz, Brian ; Abbadessa, Giovanni
Publisher:United States: Public Library of Science
Journal title:PloS one, 2016-09, Vol.11 (9), p.e0162594-e0162594
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ArticlesPeer ReviewedFull Text
Targeting AKT1-E17K and the PI3K/AKT Pathway with an Allosteric AKT Inhibitor, ARQ 092
Author / Creator:Yu, Yi ; Savage, Ronald E. ; Eathiraj, Sudharshan ; Meade, Justin ; Wick, Michael J. ; Hall, Terence ; Abbadessa, Giovanni ; Schwartz, Brian
Publisher:United States: Public Library of Science
Journal title:PloS one, 2015-10, Vol.10 (10), p.e0140479-e0140479
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ArticlesPeer ReviewedFull Text
TBC-domain GAPs for Rab GTPases accelerate GTP hydrolysis by a dual-finger mechanism
Author / Creator:Pan, Xiaojing ; Eathiraj, Sudharshan ; Munson, Mary ; Lambright, David G.
Publisher:London: Nature Publishing Group UK
Journal title:Nature, 2006-07, Vol.442 (7100), p.303-306
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ArticlesPeer ReviewedFull Text
Structural basis for Rab GTPase recognition and endosome tethering by the C₂H₂ zinc finger of Early Endosomal Autoantigen 1 (EEA1)
Author / Creator:Mishra, Ashwini ; Eathiraj, Sudharshan ; Corvera, Silvia ; Lambright, David G
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2010-06, Vol.107 (24), p.10866-10871
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ArticlesPeer ReviewedFull Text
Preclinical evaluation of combination nemtabrutinib and venetoclax in chronic lymphocytic leukemia
Author / Creator:Muhowski, Elizabeth M. ; Ravikrishnan, Janani ; Gordon, Britten ; Yu, Lianbo ; Misra, Shrilekha ; Walker, Brandi ; Eathiraj, Sudharshan ; Sampath, Deepa ; Rogers, Kerry A. ; Byrd, John C. ; Woyach, Jennifer A.
Publisher:England: BioMed Central Ltd
Journal title:Journal of hematology and oncology, 2022-11, Vol.15 (1), p.166-166, Article 166
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ArticlesPeer ReviewedFull Text
Structural basis of family-wide Rab GTPase recognition by rabenosyn-5
Author / Creator:Eathiraj, Sudharshan ; Pan, Xiaojing ; Ritacco, Christopher ; Lambright, David G.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2005-07, Vol.436 (7049), p.415-419
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ArticlesPeer ReviewedFull Text
Preclinical efficacy for a novel tyrosine kinase inhibitor, ArQule 531 against acute myeloid leukemia
Author / Creator:Elgamal, Ola A. ; Mehmood, Abeera ; Jeon, Jae Yoon ; Carmichael, Bridget ; Lehman, Amy ; Orwick, Shelley J. ; Truxall, Jean ; Goettl, Virginia M. ; Wasmuth, Ronni ; Tran, Minh ; Mitchell, Shaneice ; Lapalombella, Rosa ; Eathiraj, Sudharshan ; Schwartz, Brian ; Stegmaier, Kimberly ; Baker, Sharyn D. ; Hertlein, Erin ; Byrd, John C.
Publisher:England: BioMed Central Ltd
Journal title:Journal of hematology and oncology, 2020-01, Vol.13 (1), p.8-14, Article 8
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ArticlesPeer ReviewedFull Text
Structural basis for Rab GTPase recognition and endosome tethering by the C 2 H 2 zinc finger of Early Endosomal Autoantigen 1 (EEA1)
Author / Creator:Mishra, Ashwini ; Eathiraj, Sudharshan ; Corvera, Silvia ; Lambright, David G.
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2010-06, Vol.107 (24), p.10866-10871
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ArticlesPeer ReviewedFull Text
Structural basis for Rab GTPase recognition and endosome tethering by the C^sub 2^H^sub 2^ zinc finger of Early Endosomal Autoantigen 1 (EEA1)
Author / Creator:Mishra, Ashwini ; Eathiraj, Sudharshan ; Corvera, Silvia ; Lambright, David G
Publisher:Washington: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2010-06, Vol.107 (24), p.10866
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ArticlesPeer ReviewedFull Text
Structural basis for Rab GTPase recognition and endosome tethering by the C sub(2)H sub(2) zinc finger of Early Endosomal Autoantigen 1 (EEA1)
Author / Creator:Mishra, Ashwini ; Eathiraj, Sudharshan ; Corvera, Silvia ; Lambright, David G
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2010-06, Vol.107 (24), p.10866-10871
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ArticlesPeer ReviewedFull Text
Structural basis for Rab GTPase recognition and endosome tethering by the CâHâ zinc finger of Early Endosomal Autoantigen 1 (EEA1)
Author / Creator:Mishra, Ashwini ; Eathiraj, Sudharshan ; Corvera, Silvia ; Lambright, David G
Publisher:National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2010, Vol.107 (24), p.10866-10871
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Preclinical Activity of ARQ 087, a Novel Inhibitor Targeting FGFR Dysregulation

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Targeting AKT1-E17K and the PI3K/AKT Pathway with an Allosteric AKT Inhibitor, ARQ 092

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TBC-domain GAPs for Rab GTPases accelerate GTP hydrolysis by a dual-finger mechanism

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Structural basis for Rab GTPase recognition and endosome tethering by the C₂H₂ zinc finger of Early Endosomal Autoantigen 1 (EEA1)

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Preclinical evaluation of combination nemtabrutinib and venetoclax in chronic lymphocytic leukemia

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Structural basis of family-wide Rab GTPase recognition by rabenosyn-5

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Preclinical efficacy for a novel tyrosine kinase inhibitor, ArQule 531 against acute myeloid leukemia

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Structural basis for Rab GTPase recognition and endosome tethering by the C 2 H 2 zinc finger of Early Endosomal Autoantigen 1 (EEA1)

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Structural basis for Rab GTPase recognition and endosome tethering by the C^sub 2^H^sub 2^ zinc finger of Early Endosomal Autoantigen 1 (EEA1)

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Structural basis for Rab GTPase recognition and endosome tethering by the C sub(2)H sub(2) zinc finger of Early Endosomal Autoantigen 1 (EEA1)

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Structural basis for Rab GTPase recognition and endosome tethering by the CâHâ zinc finger of Early Endosomal Autoantigen 1 (EEA1)

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Structural basis for Rab GTPase recognition and endosome tethering by the CâHâ zinc finger of Early Endosomal Autoantigen 1 (EEA1)