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Molecular Characterization of a New ALK Translocation Involving Moesin (MSN-ALK) in Anaplastic Large...

Molecular Characterization of a New ALK Translocation Involving Moesin (MSN-ALK) in Anaplastic Large...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_755134485

Molecular Characterization of a New ALK Translocation Involving Moesin (MSN-ALK) in Anaplastic Large Cell Lymphoma

About this item

Full title

Molecular Characterization of a New ALK Translocation Involving Moesin (MSN-ALK) in Anaplastic Large Cell Lymphoma

Publisher

New York: Nature Publishing Group US

Journal title

Laboratory investigation, 2001-03, Vol.81 (3), p.419-426

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

The majority of anaplastic large cell lymphomas (ALCL) are associated with chromosomal abnormalities affecting the anaplastic lymphoma kinase (
ALK
) gene which result in the expression of hybrid ALK fusion proteins in the tumor cells. In most of these tumors, the hybrid gene comprises the 5′ region of nucleophosmin (
NPM
) fused in fra...

Alternative Titles

Full title

Molecular Characterization of a New ALK Translocation Involving Moesin (MSN-ALK) in Anaplastic Large Cell Lymphoma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_755134485

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_755134485

Other Identifiers

ISSN

0023-6837

E-ISSN

1530-0307

DOI

10.1038/labinvest.3780249

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