Microbial translocation is a cause of systemic immune activation in chronic HIV infection
Microbial translocation is a cause of systemic immune activation in chronic HIV infection
About this item
Full title
Author / Creator
Brenchley, Jason M , Price, David A , Schacker, Timothy W , Asher, Tedi E , Silvestri, Guido , Rao, Srinivas , Kazzaz, Zachary , Bornstein, Ethan , Lambotte, Olivier , Altmann, Daniel , Blazar, Bruce R , Rodriguez, Benigno , Teixeira-Johnson, Leia , Landay, Alan , Martin, Jeffrey N , Hecht, Frederick M , Picker, Louis J , Lederman, Michael M , Deeks, Steven G and Douek, Daniel C
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Chronic activation of the immune system is a hallmark of progressive HIV infection and better predicts disease outcome than plasma viral load, yet its etiology remains obscure. Here we show that circulating microbial products, probably derived from the gastrointestinal tract, are a cause of HIV-related systemic immune activation. Circulating lipopo...
Alternative Titles
Full title
Microbial translocation is a cause of systemic immune activation in chronic HIV infection
Authors, Artists and Contributors
Author / Creator
Price, David A
Schacker, Timothy W
Asher, Tedi E
Silvestri, Guido
Rao, Srinivas
Kazzaz, Zachary
Bornstein, Ethan
Lambotte, Olivier
Altmann, Daniel
Blazar, Bruce R
Rodriguez, Benigno
Teixeira-Johnson, Leia
Landay, Alan
Martin, Jeffrey N
Hecht, Frederick M
Picker, Louis J
Lederman, Michael M
Deeks, Steven G
Douek, Daniel C
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_762269303
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_762269303
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/nm1511
