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ArticlesPeer ReviewedFull Text
Acute Graft-versus-Host Disease — Biologic Process, Prevention, and Therapy
Author / Creator:Zeiser, Robert ; Blazar, Bruce R
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2017-11, Vol.377 (22), p.2167-2179
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ArticlesPeer ReviewedFull Text
Pathophysiology of Chronic Graft-versus-Host Disease and Therapeutic Targets
Author / Creator:Zeiser, Robert ; Blazar, Bruce R
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2017-12, Vol.377 (26), p.2565-2579
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ArticlesPeer ReviewedFull Text
Dissecting the biology of allogeneic HSCT to enhance the GvT effect whilst minimizing GvHD
Author / Creator:Blazar, Bruce R. ; Hill, Geoffrey R. ; Murphy, William J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Clinical oncology, 2020-08, Vol.17 (8), p.475-492
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Newsletter articlesFull Text
Blazar Bruce R, Griffin John H, Flynn Ryan P, Sinha Ranjeet K, Regents of the University of Minnesota and The Scripps Research Institute Seek Patent for Materials and Methods for Treating or Preventin...
Publisher:New Delhi: Pedia Content Solutions Pvt. Ltd
Journal title:Global IP News. Pharmaceutical Patent News, 2020
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ArticlesPeer ReviewedFull Text
Chronic stimulation drives human NK cell dysfunction and epigenetic reprograming
Author / Creator:Merino, Aimee ; Zhang, Bin ; Dougherty, Philip ; Luo, Xianghua ; Wang, Jinhua ; Blazar, Bruce R ; Miller, Jeffrey S ; Cichocki, Frank
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2019-09, Vol.130 (9), p.3770-3785
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ArticlesPeer ReviewedFull Text
Virus-specific memory T cells populate tumors and can be repurposed for tumor immunotherapy
Author / Creator:Rosato, Pamela C. ; Wijeyesinghe, Sathi ; Stolley, J. Michael ; Nelson, Christine E. ; Davis, Rachel L. ; Manlove, Luke S. ; Pennell, Christopher A. ; Blazar, Bruce R. ; Chen, Clark C. ; Geller, Melissa A. ; Vezys, Vaiva ; Masopust, David
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-02, Vol.10 (1), p.567-567, Article 567
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ArticlesPeer ReviewedFull Text
Cytokine mediators of chronic graft-versus-host disease
Author / Creator:MacDonald, Kelli Pa ; Blazar, Bruce R ; Hill, Geoffrey R
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2017-06, Vol.127 (7), p.2452-2463
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ArticlesPeer ReviewedFull Text
A trispecific killer engager molecule against CLEC12A effectively induces NK-cell mediated killing of AML cells
Author / Creator:Arvindam, Upasana Sunil ; van Hauten, Paulien M. M. ; Schirm, Dawn ; Schaap, Nicolaas ; Hobo, Willemijn ; Blazar, Bruce R. ; Vallera, Daniel A. ; Dolstra, Harry ; Felices, Martin ; Miller, Jeffrey S.
Publisher:London: Nature Publishing Group UK
Journal title:Leukemia, 2021-06, Vol.35 (6), p.1586-1596
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ArticlesPeer ReviewedFull Text
The lineage stability and suppressive program of regulatory T cells require protein O-GlcNAcylation
Author / Creator:Liu, Bing ; Salgado, Oscar C. ; Singh, Sangya ; Hippen, Keli L. ; Maynard, Jason C. ; Burlingame, Alma L. ; Ball, Lauren E. ; Blazar, Bruce R. ; Farrar, Michael A. ; Hogquist, Kristin A. ; Ruan, Hai-Bin
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-01, Vol.10 (1), p.354-354, Article 354
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ArticlesPeer ReviewedFull Text
Immune dysfunction signatures predict outcomes and define checkpoint blockade-unresponsive microenvironments in acute myeloid leukemia
Author / Creator:Rutella, Sergio ; Vadakekolathu, Jayakumar ; Mazziotta, Francesco ; Reeder, Stephen ; Yau, Tung-On ; Mukhopadhyay, Rupkatha ; Dickins, Benjamin ; Altmann, Heidi ; Kramer, Michael ; Knaus, Hanna A ; Blazar, Bruce R ; Radojcic, Vedran ; Zeidner, Joshua F ; Arruda, Andrea ; Wang, Bofei ; Abbas, Hussein A ; Minden, Mark D ; Tasian, Sarah K ; Bornhäuser, Martin ; Gojo, Ivana ; Luznik, Leo
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2022-11, Vol.132 (21), p.1-20
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ArticlesPeer ReviewedFull Text
Evaluation of TCR Gene Editing Achieved by TALENs, CRISPR/Cas9, and megaTAL Nucleases
Author / Creator:Osborn, Mark J ; Webber, Beau R ; Knipping, Friederike ; Lonetree, Cara-lin ; Tennis, Nicole ; DeFeo, Anthony P ; McElroy, Amber N ; Starker, Colby G ; Lee, Catherine ; Merkel, Sarah ; Lund, Troy C ; Kelly-Spratt, Karen S ; Jensen, Michael C ; Voytas, Daniel F ; von Kalle, Christof ; Schmidt, Manfred ; Gabriel, Richard ; Hippen, Keli L ; Miller, Jeffrey S ; Scharenberg, Andrew M ; Tolar, Jakub ; Blazar, Bruce R
Publisher:United States: Elsevier Inc
Journal title:Molecular therapy, 2016-03, Vol.24 (3), p.570-581
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ArticlesPeer ReviewedFull Text
Plasmacytoid dendritic cells from mouse tumor-draining lymph nodes directly activate mature Tregs via indoleamine 2,3-dioxygenase
Author / Creator:Sharma, Madhav D ; Baban, Babak ; Chandler, Phillip ; Hou, De-Yan ; Singh, Nagendra ; Yagita, Hideo ; Azuma, Miyuki ; Blazar, Bruce R ; Mellor, Andrew L ; Munn, David H
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2007-09, Vol.117 (9), p.2570-2582
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ArticlesPeer ReviewedFull Text
Selective oral ROCK2 inhibitor down-regulates IL-21 and IL-17 secretion in human T cells via STAT3-dependent mechanism
Author / Creator:Zanin-Zhorov, Alexandra ; Weiss, Jonathan M. ; Nyuydzefe, Melanie S. ; Chen, Wei ; Scher, Jose U. ; Mo, Rigen ; Depoil, David ; Rao, Nishta ; Liu, Ben ; Wei, Jianlu ; Lucas, Sarah ; Koslow, Matthew ; Roche, Maria ; Schueller, Olivier ; Weiss, Sara ; Poyurovsky, Masha V. ; Tonra, James ; Hippen, Keli L ; Dustin, Michael L. ; Blazar, Bruce R. ; Liu, Chuan-ju ; Waksal, Samuel D. ; Dinarello, Charles A.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2014-11, Vol.111 (47), p.16814-16819
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ArticlesPeer ReviewedFull Text
PD-L1 signaling selectively regulates T cell lymphatic transendothelial migration
Author / Creator:Piao, Wenji ; Li, Lushen ; Saxena, Vikas ; Iyyathurai, Jegan ; Lakhan, Ram ; Zhang, Yigang ; Lape, Isadora Tadeval ; Paluskievicz, Christina ; Hippen, Keli L. ; Lee, Young ; Silverman, Emma ; Shirkey, Marina W. ; Riella, Leonardo V. ; Blazar, Bruce R. ; Bromberg, Jonathan S.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-04, Vol.13 (1), p.2176-15, Article 2176
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ArticlesPeer ReviewedFull Text
Graft-versus-host disease of the CNS is mediated by TNF upregulation in microglia
Author / Creator:Mathew, Nimitha R ; Vinnakota, Janaki M ; Apostolova, Petya ; Erny, Daniel ; Hamarsheh, Shaimaa ; Andrieux, Geoffroy ; Kim, Jung-Seok ; Hanke, Kathrin ; Goldmann, Tobias ; Chappell-Maor, Louise ; El-Khawanky, Nadia ; Ihorst, Gabriele ; Schmidt, Dominik ; Duyster, Justus ; Finke, Jürgen ; Blank, Thomas ; Boerries, Melanie ; Blazar, Bruce R ; Jung, Steffen ; Prinz, Marco ; Zeiser, Robert
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2020-03, Vol.130 (3), p.1315-1329
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ArticlesPeer ReviewedFull Text
Development of a Decellularized Lung Bioreactor System for Bioengineering the Lung: The Matrix Reloaded
Author / Creator:Price, Andrew P. ; England, Kristen A. ; Matson, Amy M. ; Blazar, Bruce R. ; Panoskaltsis-Mortari, Angela
Publisher:United States: Mary Ann Liebert, Inc
Journal title:Tissue engineering. Part A, 2010-08, Vol.16 (8), p.2581-2591
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ArticlesPeer ReviewedFull Text
Microbial translocation is a cause of systemic immune activation in chronic HIV infection
Author / Creator:Brenchley, Jason M ; Price, David A ; Schacker, Timothy W ; Asher, Tedi E ; Silvestri, Guido ; Rao, Srinivas ; Kazzaz, Zachary ; Bornstein, Ethan ; Lambotte, Olivier ; Altmann, Daniel ; Blazar, Bruce R ; Rodriguez, Benigno ; Teixeira-Johnson, Leia ; Landay, Alan ; Martin, Jeffrey N ; Hecht, Frederick M ; Picker, Louis J ; Lederman, Michael M ; Deeks, Steven G ; Douek, Daniel C
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2006-12, Vol.12 (12), p.1365-1371
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ArticlesPeer ReviewedFull Text
Bone Marrow Transplantation for Recessive Dystrophic Epidermolysis Bullosa
Author / Creator:Wagner, John E ; Ishida-Yamamoto, Akemi ; McGrath, John A ; Hordinsky, Maria ; Keene, Douglas R ; Woodley, David T ; Chen, Mei ; Riddle, Megan J ; Osborn, Mark J ; Lund, Troy ; Dolan, Michelle ; Blazar, Bruce R ; Tolar, Jakub
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2010-08, Vol.363 (7), p.629-639
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ArticlesPeer ReviewedFull Text
IL-33 acts as a costimulatory signal to generate alloreactive Th1 cells in graft-versus-host disease
Author / Creator:Dwyer, Gaelen K ; Mathews, Lisa R ; Villegas, José A ; Lucas, Anna ; Gonzalez de Peredo, Anne ; Blazar, Bruce R ; Girard, Jean-Philippe ; Poholek, Amanda C ; Luther, Sanjiv A ; Shlomchik, Warren ; Turnquist, Hēth R
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2022-06, Vol.132 (12), p.1-16
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ArticlesPeer ReviewedFull Text
A tissue-intrinsic IL-33/EGF circuit promotes epithelial regeneration after intestinal injury
Author / Creator:Calafiore, Marco ; Fu, Ya-Yuan ; Vinci, Paola ; Arnhold, Viktor ; Chang, Winston Y. ; Jansen, Suze A. ; Egorova, Anastasiya ; Takashima, Shuichiro ; Kuttiyara, Jason ; Ito, Takahiro ; Serody, Jonathan ; Nakae, Susumu ; Turnquist, Heth ; van Es, Johan ; Clevers, Hans ; Lindemans, Caroline A. ; Blazar, Bruce R. ; Hanash, Alan M.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-09, Vol.14 (1), p.5411-13, Article 5411
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Acute Graft-versus-Host Disease — Biologic Process, Prevention, and Therapy

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Pathophysiology of Chronic Graft-versus-Host Disease and Therapeutic Targets

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Dissecting the biology of allogeneic HSCT to enhance the GvT effect whilst minimizing GvHD

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Blazar Bruce R, Griffin John H, Flynn Ryan P, Sinha Ranjeet K, Regents of the University of Minnesota and The Scripps Research Institute Seek Patent for Materials and Methods for Treating or Preventin...

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Chronic stimulation drives human NK cell dysfunction and epigenetic reprograming

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Virus-specific memory T cells populate tumors and can be repurposed for tumor immunotherapy

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Cytokine mediators of chronic graft-versus-host disease

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A trispecific killer engager molecule against CLEC12A effectively induces NK-cell mediated killing of AML cells

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The lineage stability and suppressive program of regulatory T cells require protein O-GlcNAcylation

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Immune dysfunction signatures predict outcomes and define checkpoint blockade-unresponsive microenvironments in acute myeloid leukemia

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Evaluation of TCR Gene Editing Achieved by TALENs, CRISPR/Cas9, and megaTAL Nucleases

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Plasmacytoid dendritic cells from mouse tumor-draining lymph nodes directly activate mature Tregs via indoleamine 2,3-dioxygenase

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Selective oral ROCK2 inhibitor down-regulates IL-21 and IL-17 secretion in human T cells via STAT3-dependent mechanism

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PD-L1 signaling selectively regulates T cell lymphatic transendothelial migration

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Graft-versus-host disease of the CNS is mediated by TNF upregulation in microglia

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Development of a Decellularized Lung Bioreactor System for Bioengineering the Lung: The Matrix Reloaded

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Microbial translocation is a cause of systemic immune activation in chronic HIV infection

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Bone Marrow Transplantation for Recessive Dystrophic Epidermolysis Bullosa

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IL-33 acts as a costimulatory signal to generate alloreactive Th1 cells in graft-versus-host disease

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A tissue-intrinsic IL-33/EGF circuit promotes epithelial regeneration after intestinal injury

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