OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis
OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis
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Kong, Young-Yun , Yoshida, Hiroki , Sarosi, Ildiko , Tan, Hong-Lin , Timms, Emma , Capparelli, Casey , Morony, Sean , Oliveira-dos-Santos, Antonio J. , Van, Gwyneth , Itie, Annick , Khoo, Wilson , Wakeham, Andrew , Dunstan, Colin R. , Lacey, David L. , Mak, Tak W. , Boyle, William J. and Penninger, Josef M.
Publisher
London: Nature Publishing Group UK
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English
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Publisher
London: Nature Publishing Group UK
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Contents
The tumour-necrosis-factor-family molecule osteoprotegerin ligand (OPGL; also known as TRANCE, RANKL and ODF) has been identified as a potential osteoclast differentiation factor and regulator of interactions between T cells and dendritic cells
in vitro
. Mice with a disrupted
opgl
gene show severe osteopetrosis and a defect in tooth er...
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Full title
OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis
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TN_cdi_proquest_miscellaneous_762269599
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_762269599
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/16852
