Activating gene expression in mammalian cells with promoter-targeted duplex RNAs
Activating gene expression in mammalian cells with promoter-targeted duplex RNAs
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
The ability to selectively activate or inhibit gene expression is fundamental to understanding complex cellular systems and developing therapeutics. Recent studies have demonstrated that duplex RNAs complementary to promoters within chromosomal DNA are potent gene silencing agents in mammalian cells. Here we report that chromosome-targeted RNAs als...
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Full title
Activating gene expression in mammalian cells with promoter-targeted duplex RNAs
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TN_cdi_proquest_miscellaneous_762270229
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_762270229
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ISSN
1552-4450
E-ISSN
1552-4469
DOI
10.1038/nchembio860
