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Specific interference with gene function by double-stranded RNA in early mouse development

Specific interference with gene function by double-stranded RNA in early mouse development

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_762270475

Specific interference with gene function by double-stranded RNA in early mouse development

About this item

Full title

Specific interference with gene function by double-stranded RNA in early mouse development

Publisher

London: Nature Publishing Group UK

Journal title

Nature cell biology, 2000-02, Vol.2 (2), p.70-75

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The use of double-stranded (ds) RNA is a powerful way of interfering with gene expression in a range of organisms, but doubts have been raised about whether it could be successful in mammals. Here, we show that dsRNA is effective as a specific inhibitor of the function of three genes in the mouse, namely maternally expressed c-
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in the ooc...

Alternative Titles

Full title

Specific interference with gene function by double-stranded RNA in early mouse development

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_762270475

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_762270475

Other Identifiers

ISSN

1465-7392,1476-4679

E-ISSN

1476-4679

DOI

10.1038/35000016

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