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Dynamic modeling of imatinib-treated chronic myeloid leukemia: functional insights and clinical impl...

Dynamic modeling of imatinib-treated chronic myeloid leukemia: functional insights and clinical impl...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_762277590

Dynamic modeling of imatinib-treated chronic myeloid leukemia: functional insights and clinical implications

About this item

Full title

Dynamic modeling of imatinib-treated chronic myeloid leukemia: functional insights and clinical implications

Publisher

New York: Nature Publishing Group US

Journal title

Nature medicine, 2006-10, Vol.12 (10), p.1181-1184

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Treatment of chronic myeloid leukemia (CML) with the tyrosine kinase inhibitor imatinib represents a successful application of molecularly targeted cancer therapy. A rapid hematologic and cytogenetic response can be induced in the majority of people, even in advanced disease. However, complete eradication of malignant cells, which are characterized...

Alternative Titles

Full title

Dynamic modeling of imatinib-treated chronic myeloid leukemia: functional insights and clinical implications

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_762277590

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_762277590

Other Identifiers

ISSN

1078-8956

E-ISSN

1546-170X

DOI

10.1038/nm1487

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