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A cell initiating human acute myeloid leukaemia after transplantation into SCID mice

A cell initiating human acute myeloid leukaemia after transplantation into SCID mice

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_76358513

A cell initiating human acute myeloid leukaemia after transplantation into SCID mice

About this item

Full title

A cell initiating human acute myeloid leukaemia after transplantation into SCID mice

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 1994-02, Vol.367 (6464), p.645-648

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

MOST human acute myeloid leukaemia (AML) cells have limited proliferative capacity, suggesting that the leukaemic clone may be maintained by a rare population of stem cells
1–5
. This putative leukaemic stem cell has not been characterized because the available
in vitro
assays can only detect progenitors with limited proliferative and r...

Alternative Titles

Full title

A cell initiating human acute myeloid leukaemia after transplantation into SCID mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_76358513

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_76358513

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/367645a0

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