Transformation and Plasmacytoid Differentiation of EBV-Infected Human B Lymphoblasts by ras Oncogene...
Transformation and Plasmacytoid Differentiation of EBV-Infected Human B Lymphoblasts by ras Oncogenes
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Washington, DC: The American Association for the Advancement of Science
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Language
English
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Washington, DC: The American Association for the Advancement of Science
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The biological effects of ras oncogene activation in B cells were studied by using amphotropic retroviral vectors to introduce H- or N-ras oncogenes into human B lymphoblasts immortalized by Epstein-Barr virus. Expression of both H- and N-ras oncogenes led to malignant transformation of these cells, as shown by clonogenicity in semisolid media and...
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Transformation and Plasmacytoid Differentiation of EBV-Infected Human B Lymphoblasts by ras Oncogenes
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TN_cdi_proquest_miscellaneous_78852381
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_78852381
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ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.2536954