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Transformation and Plasmacytoid Differentiation of EBV-Infected Human B Lymphoblasts by ras Oncogene...

Transformation and Plasmacytoid Differentiation of EBV-Infected Human B Lymphoblasts by ras Oncogene...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_78852381

Transformation and Plasmacytoid Differentiation of EBV-Infected Human B Lymphoblasts by ras Oncogenes

About this item

Full title

Transformation and Plasmacytoid Differentiation of EBV-Infected Human B Lymphoblasts by ras Oncogenes

Publisher

Washington, DC: The American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 1989-02, Vol.243 (4891), p.660-663

Language

English

Formats

Publication information

Publisher

Washington, DC: The American Association for the Advancement of Science

More information

Scope and Contents

Contents

The biological effects of ras oncogene activation in B cells were studied by using amphotropic retroviral vectors to introduce H- or N-ras oncogenes into human B lymphoblasts immortalized by Epstein-Barr virus. Expression of both H- and N-ras oncogenes led to malignant transformation of these cells, as shown by clonogenicity in semisolid media and...

Alternative Titles

Full title

Transformation and Plasmacytoid Differentiation of EBV-Infected Human B Lymphoblasts by ras Oncogenes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_78852381

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_78852381

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.2536954

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