Cloning of a 67-kD neutrophil oxidase factor with similarity to a noncatalytic region of p60c-src
Cloning of a 67-kD neutrophil oxidase factor with similarity to a noncatalytic region of p60c-src
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Author / Creator
Leto, T L , Lomax, K J , Volpp, B D , Nunoi, H , Sechler, J M , Nauseef, W M , Clark, R A , Gallin, J I and Malech, H L
Publisher
United States: American Association for the Advancement of Science
Journal title
Language
English
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Publication information
Publisher
United States: American Association for the Advancement of Science
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Scope and Contents
Contents
Chronic granulomatous diseases (CGDs) are characterized by recurrent infections resulting from impaired superoxide production by a phagocytic cell, nicotinamide adenine dinucleotide phosphate (reduced) (NADPH) oxidase. Complementary DNAs were cloned that encode the 67-kilodalton (kD) cytosolic oxidase factor (p67), which is deficient in 5% of CGD p...
Alternative Titles
Full title
Cloning of a 67-kD neutrophil oxidase factor with similarity to a noncatalytic region of p60c-src
Authors, Artists and Contributors
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Record Identifier
TN_cdi_proquest_miscellaneous_79750760
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_79750760
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1692159