Progression from lymphoid hyperplasia to high-grade malignant lymphoma in mice transgenic for the t(...
Progression from lymphoid hyperplasia to high-grade malignant lymphoma in mice transgenic for the t(14; 18)
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London: Nature Publishing
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English
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London: Nature Publishing
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Follicular lymphoma, the most common human lymphoma, characteristically has a t(14; 18) interchromosomal translocation. It is typically an indolent disease comprised of small resting B cells, but frequently develops into a high-grade lymphoma. The t(14; 18) translocates the Bcl-2 gene, generating a deregulated Bcl-2-immunoglobulin fusion gene. Bcl-...
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Full title
Progression from lymphoid hyperplasia to high-grade malignant lymphoma in mice transgenic for the t(14; 18)
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TN_cdi_proquest_miscellaneous_80417853
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_80417853
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/349254a0
