Graft-versus-host disease is enhanced by extracellular ATP activating P2X7R
Graft-versus-host disease is enhanced by extracellular ATP activating P2X7R
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Author / Creator
Wilhelm, Konrad , Ganesan, Jayanthi , Müller, Tobias , Dürr, Christoph , Grimm, Melanie , Beilhack, Andreas , Krempl, Christine D , Sorichter, Stephan , Gerlach, Ulrike V , Jüttner, Eva , Zerweck, Alf , Gärtner, Frank , Pellegatti, Patrizia , Di Virgilio, Francesco , Ferrari, Davide , Kambham, Neeraja , Fisch, Paul , Finke, Jürgen , Idzko, Marco and Zeiser, Robert
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publication information
Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
By acting on the P2X
7
receptor, ATP released upon cell damage functions as a danger signal to promote acute graft-versus-host disease after bone marrow transplantation in mice.
Danger signals released upon cell damage can cause excessive immune-mediated tissue destruction such as that found in acute graft-versus-host disease (GVHD), allog...
Alternative Titles
Full title
Graft-versus-host disease is enhanced by extracellular ATP activating P2X7R
Authors, Artists and Contributors
Author / Creator
Ganesan, Jayanthi
Müller, Tobias
Dürr, Christoph
Grimm, Melanie
Beilhack, Andreas
Krempl, Christine D
Sorichter, Stephan
Gerlach, Ulrike V
Jüttner, Eva
Zerweck, Alf
Gärtner, Frank
Pellegatti, Patrizia
Di Virgilio, Francesco
Ferrari, Davide
Kambham, Neeraja
Fisch, Paul
Finke, Jürgen
Idzko, Marco
Zeiser, Robert
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_816530668
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_816530668
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/nm.2242
