Activating mutations in NOTCH1 in acute myeloid leukemia and lineage switch leukemias
Activating mutations in NOTCH1 in acute myeloid leukemia and lineage switch leukemias
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Author / Creator
PALOMERO, T , MCKENNA, K , ASTER, J. C , LOOK, A. T , FERRANDO, A. A , O-NEIL, J , GALINSKY, I , STONE, R , SUZUKAWA, K , STIAKAKI, E , KALMANTI, M , FOX, E. A and CALIGIURI, M. A
Publisher
London: Nature Publishing
Journal title
Language
English
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Publisher
London: Nature Publishing
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Scope and Contents
Contents
Activating mutations in NOTCH1 are found in over 50% of human T-cell lymphoblastic leukemias (T-ALLs). Here, we report the analysis for activating NOTCH1 mutations in a large number of acute myeloid leukemia (AML) primary samples and cell lines. We found activating mutations in NOTCH1 in a single M0 primary AML sample, in three (ML1, ML2 and CTV-1)...
Alternative Titles
Full title
Activating mutations in NOTCH1 in acute myeloid leukemia and lineage switch leukemias
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Record Identifier
TN_cdi_proquest_miscellaneous_817602995
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_817602995
Other Identifiers
ISSN
0887-6924
E-ISSN
1476-5551
DOI
10.1038/sj.leu.2404409
