Distribution study of peplomycin in rat kidney revealed by immunocytochemistry using monoclonal anti...
Distribution study of peplomycin in rat kidney revealed by immunocytochemistry using monoclonal antibodies
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Publisher
Berlin/Heidelberg: Berlin/Heidelberg : Springer-Verlag
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Language
English
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Publisher
Berlin/Heidelberg: Berlin/Heidelberg : Springer-Verlag
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Contents
Peplomycin (PEP), an anti-tumor antibiotic related structurally to bleomycin, is widely used, especially for squamous cell carcinoma but shows renal toxicity. We prepared monoclonal antibodies (mAbs) against N-(γ-maleimidobutyryloxy)succinimide-conjugated PEP. The mAbs were monospecific for PEP, but did not react with bleomycin and other anticancer...
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Full title
Distribution study of peplomycin in rat kidney revealed by immunocytochemistry using monoclonal antibodies
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TN_cdi_proquest_miscellaneous_839715165
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_839715165
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ISSN
0948-6143
E-ISSN
1432-119X
DOI
10.1007/s00418-010-0768-9
