DRD2/AKT1 interaction on D2 c-AMP independent signaling, attentional processing, and response to ola...
DRD2/AKT1 interaction on D2 c-AMP independent signaling, attentional processing, and response to olanzapine treatment in schizophrenia
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Author / Creator
Blasi, Giuseppe , Napolitano, Francesco , Ursini, Gianluca , Taurisano, Paolo , Romano, Raffaella , Caforio, Grazia , Fazio, Leonardo , Gelao, Barbara , Di Giorgio, Annabella , Iacovelli, Luisa , Sinibaldi, Lorenzo , Popolizio, Teresa , Usiello, Alessandro , Bertolino, Alessandro and Weinberger, Daniel R.
Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publisher
United States: National Academy of Sciences
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Contents
The D2/AKT1/GSK-3β signaling pathway has been involved in the downstream intracellular effects of dopamine, in the pathophysiology of cognitive deficits and related brain activity in schizophrenia, as well as in response to treatment with antipsychotics. Polymorphisms in the D2 (DRD2 rs1076560) and AKT1 (AKT1 rs1130233) genes have been associated w...
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Full title
DRD2/AKT1 interaction on D2 c-AMP independent signaling, attentional processing, and response to olanzapine treatment in schizophrenia
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Record Identifier
TN_cdi_proquest_miscellaneous_845765882
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_845765882
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1013535108
