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The adaptor protein CARD9 is essential for the activation of myeloid cells through ITAM-associated a...

The adaptor protein CARD9 is essential for the activation of myeloid cells through ITAM-associated a...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_851461552

The adaptor protein CARD9 is essential for the activation of myeloid cells through ITAM-associated and Toll-like receptors

About this item

Full title

The adaptor protein CARD9 is essential for the activation of myeloid cells through ITAM-associated and Toll-like receptors

Publisher

New York: Nature Publishing Group US

Journal title

Nature Immunology, 2007-06, Vol.8 (6), p.619-629

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Immunoreceptor tyrosine-based activation motifs (ITAMs) are crucial in antigen receptor signaling in acquired immunity. Although receptors associated with the ITAM-bearing adaptors FcRγ and DAP12 on myeloid cells have been suggested to activate innate immune responses, the mechanism coupling those receptors to 'downstream' signaling events is uncle...

Alternative Titles

Full title

The adaptor protein CARD9 is essential for the activation of myeloid cells through ITAM-associated and Toll-like receptors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_851461552

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_851461552

Other Identifiers

ISSN

1529-2908

E-ISSN

1529-2916,1365-2567

DOI

10.1038/ni1466

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