Stat3 controls lysosomal-mediated cell death in vivo
Stat3 controls lysosomal-mediated cell death in vivo
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Post-lactational involution in the mammary gland is shown to be accomplished by a lysosome-mediated cell death pathway. This pathway is independent of the executioner caspases 3, 6 and 7, and instead relies on Stat3-mediated upregulation of cathepsins.
It is well established that lysosomes play an active role during the execution of cell death
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Full title
Stat3 controls lysosomal-mediated cell death in vivo
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TN_cdi_proquest_miscellaneous_855198283
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_855198283
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ISSN
1465-7392
E-ISSN
1476-4679
DOI
10.1038/ncb2171
