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Control of the Metabolic Switch in Cancers by Oncogenes and Tumor Suppressor Genes

Control of the Metabolic Switch in Cancers by Oncogenes and Tumor Suppressor Genes

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_855689988

Control of the Metabolic Switch in Cancers by Oncogenes and Tumor Suppressor Genes

About this item

Full title

Control of the Metabolic Switch in Cancers by Oncogenes and Tumor Suppressor Genes

Publisher

United States: American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 2010-12, Vol.330 (6009), p.1340-1344

Language

English

Formats

Publication information

Publisher

United States: American Association for the Advancement of Science

More information

Scope and Contents

Contents

Cells from some tumors use an altered metabolic pattern compared with that of normal differentiated adult cells in the body. Tumor cells take up much more glucose and mainly process it through aerobic glycolysis, producing large quantities of secreted lactate with a lower use of oxidative phosphorylation that would generate more adenosine triphosph...

Alternative Titles

Full title

Control of the Metabolic Switch in Cancers by Oncogenes and Tumor Suppressor Genes

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_855689988

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_855689988

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.1193494

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