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Hedgehog-responsive candidate cell of origin for diffuse intrinsic pontine glioma

Hedgehog-responsive candidate cell of origin for diffuse intrinsic pontine glioma

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_857483766

Hedgehog-responsive candidate cell of origin for diffuse intrinsic pontine glioma

About this item

Full title

Hedgehog-responsive candidate cell of origin for diffuse intrinsic pontine glioma

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2011-03, Vol.108 (11), p.4453-4458

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Diffuse intrinsic pontine gliomas (DIPGs) are highly aggressive tumors of childhood that are almost universally fatal. Our understanding of this devastating cancer is limited by a dearth of available tissue for study and by the lack of a faithful animal model. Intriguingly, DIPGs are restricted to the ventral pons and occur during a narrow window o...

Alternative Titles

Full title

Hedgehog-responsive candidate cell of origin for diffuse intrinsic pontine glioma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_857483766

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_857483766

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1101657108

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