ADAM10 is the physiologically relevant, constitutive [alpha]-secretase of the amyloid precursor prot...
ADAM10 is the physiologically relevant, constitutive [alpha]-secretase of the amyloid precursor protein in primary neurons
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New York: Springer Nature B.V
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English
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New York: Springer Nature B.V
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The amyloid precursor protein (APP) undergoes constitutive shedding by a protease activity called alpha-secretase. This is considered an important mechanism preventing the generation of the Alzheimer's disease amyloid-beta peptide (Abeta). alpha-Secretase appears to be a metalloprotease of the ADAM family, but its identity remains to be established...
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ADAM10 is the physiologically relevant, constitutive [alpha]-secretase of the amyloid precursor protein in primary neurons
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TN_cdi_proquest_miscellaneous_860371191
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_860371191
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ISSN
0261-4189
E-ISSN
1460-2075
DOI
10.1038/emboj.2010.167
