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Loss of E2F7 Expression Is an Early Event in Squamous Differentiation and Causes Derepression of the...

Loss of E2F7 Expression Is an Early Event in Squamous Differentiation and Causes Derepression of the...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_862271743

Loss of E2F7 Expression Is an Early Event in Squamous Differentiation and Causes Derepression of the Key Differentiation Activator Sp1

About this item

Full title

Loss of E2F7 Expression Is an Early Event in Squamous Differentiation and Causes Derepression of the Key Differentiation Activator Sp1

Publisher

New York, NY: Elsevier Inc

Journal title

Journal of investigative dermatology, 2011-05, Vol.131 (5), p.1077-1084

Language

English

Formats

Publication information

Publisher

New York, NY: Elsevier Inc

More information

Scope and Contents

Contents

Squamous differentiation is controlled by key transcription factors such as Sp1 and E2F. We have previously shown that E2F1 can suppress transcription of the differentiation-specific gene, transglutaminase type 1 (TG1), by an indirect mechanism mediated by Sp1. Transient transfection of E2F1–E2F6 indicated that E2F-mediated reduction of Sp1 transcr...

Alternative Titles

Full title

Loss of E2F7 Expression Is an Early Event in Squamous Differentiation and Causes Derepression of the Key Differentiation Activator Sp1

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_862271743

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_862271743

Other Identifiers

ISSN

0022-202X

E-ISSN

1523-1747

DOI

10.1038/jid.2010.430

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