Cholesterol modulates glycolipid conformation and receptor activity
Cholesterol modulates glycolipid conformation and receptor activity
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Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
Experiments on reconstituted liposomes and sperm capacitation, an activation process involving the reduction in membrane cholesterol content and subsequent exposure of surface carbohydrate, show that cholesterol masks the presentation of glycolipid head groups by inducing a conformational shift in the glycan moiety.
We document a new dimension o...
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Full title
Cholesterol modulates glycolipid conformation and receptor activity
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TN_cdi_proquest_miscellaneous_862793413
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_862793413
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ISSN
1552-4450
E-ISSN
1552-4469
DOI
10.1038/nchembio.551
