VEGF regulates haematopoietic stem cell survival by an internal autocrine loop mechanism
VEGF regulates haematopoietic stem cell survival by an internal autocrine loop mechanism
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Publisher
London: Nature Publishing
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Language
English
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Publisher
London: Nature Publishing
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Contents
Vascular endothelial growth factor (VEGF) is a principal regulator of blood vessel formation and haematopoiesis, but the mechanisms by which VEGF differentially regulates these processes have been elusive. Here we describe a regulatory loop by which VEGF controls survival of haematopoietic stem cells (HSCs). We observed a reduction in survival, col...
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Full title
VEGF regulates haematopoietic stem cell survival by an internal autocrine loop mechanism
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TN_cdi_proquest_miscellaneous_864949284
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_864949284
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature00821
