The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response
The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Activation of inflammasomes leads to maturation of the pro-inflammatory cytokine IL-1β; this study adds DNA to the growing list of exogenous and endogenous inflammasome activators.
The innate immune system recognizes nucleic acids during infection and tissue damage. Whereas viral RNA is detected by endosomal toll-like receptors (TLR3, TLR7, TLR8...
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Full title
The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response
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TN_cdi_proquest_miscellaneous_864950114
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_864950114
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ISSN
0028-0836
E-ISSN
1476-4687,1476-4679
DOI
10.1038/nature06664
