GABA uptake regulates cortical excitability via cell type–specific tonic inhibition
GABA uptake regulates cortical excitability via cell type–specific tonic inhibition
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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GABA
A
receptors can mediate both 'phasic' synaptic inhibition and a persistent 'tonic' form of signaling. We show that, in the presence of intact GABA uptake, guinea pig hippocampal interneurons, but not pyramidal cells, express a tonic GABA
A
receptor–mediated conductance. This conductance was pharmacologically distinct from spontaneo...
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Full title
GABA uptake regulates cortical excitability via cell type–specific tonic inhibition
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TN_cdi_proquest_miscellaneous_864952179
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_864952179
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ISSN
1097-6256
E-ISSN
1546-1726
DOI
10.1038/nn1043
